RT info:eu-repo/semantics/article
T1 Risk factors for bacteremia and Its clinical impact on complicated community-acquired urinary tract infection
A1 Madrazo, Manuel
A1 López Cruz, Ian
A1 Piles, Laura
A1 Artero, Silvia
A1 Alberola, Juan
A1 Aguilera, Juan Alberto
A1 Eiros Bouza, José María
A1 Artero, Arturo
K1 Risk factors
K1 Bacteremia
K1 Urinary tract infections
K1 Vías urinarias - Infecciones
K1 Urinario, Aparato - Infecciones
K1 Urology
K1 Microbiology
K1 Public health
K1 3213.16 Urología
K1 32 Ciencias Médicas
K1 2414 Microbiología
K1 3212 Salud Publica
AB Bacteremia has been associated with severity in some infections; however, its impact on the prognosis of urinary tract infections (UTIs) is still disputed. Our goal is to determine the risk factors for bacteremia and its clinical impact on hospitalized patients with complicated community-acquired urinary tract infections. We conducted a prospective observational study of patients admitted to the hospital with complicated community-acquired UTIs. Clinical variables and outcomes of patients with and without bacteremia were compared, and multivariate analysis was performed to identify risk factors for bacteremia and mortality. Of 279 patients with complicated community-acquired UTIs, 37.6% had positive blood cultures. Risk factors for bacteremia by multivariate analysis were temperature ≥ 38 °C (p = 0.006, OR 1.3 (95% CI 1.1–1.7)) and procalcitonin ≥ 0.5 ng/mL (p = 0.005, OR 8.5 (95% CI 2.2–39.4)). In-hospital and 30-day mortality were 9% and 13.6%, respectively. Quick SOFA (p = 0.030, OR 5.4 (95% CI 1.2–24.9)) and Barthel Index <40% (p = 0.020, OR 4.8 (95% CI 1.3–18.2)) were associated with 30-day mortality by multivariate analysis. However, bacteremia was not associated with 30-day mortality (p = 0.154, OR 2.7 (95% CI 0.7–10.3)). Our study found that febrile community-acquired UTIs and elevated procalcitonin were risk factors for bacteremia. The outcomes in patients with bacteremia were slightly worse, but without significant differences in mortality.
PB MDPI
SN 2076-2607
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/67686
UL https://uvadoc.uva.es/handle/10324/67686
LA eng
NO Microorganisms, 2023, Vol. 11, Nº. 8, 1995
NO Producción Científica
DS UVaDOC
RD 21-jun-2024