RT info:eu-repo/semantics/article
T1 Evaluación de signos tomográficos no exudativos en casos de degeneración macular asociada a la edad de tipo exudativo
A1 Monje Fernandez, L
A1 Gallego Pinazo, R
A1 Cordero Coma, M
A1 Donate López, J
A1 Coco Martín, Rosa María
A1 Dolz Marco, R
K1 Age macular degeneration Neovascularization Pseudocyst Outer retinal tubulation Optical coherence tomography Pseudoswelling Subretinal cleft Onion sign Macular atrophy
K1 3201.09 Oftalmología
AB ABSTRACT. OBJECTIVE: To analyze the prevalence of non-exudative tomographic signs (onion sign, pseudoswelling, external retinal tubulation, pseudocysts, subretinal clefts and macular atrophy) in patients with neovascular age-related macular degeneration. MATERIAL AND METHODS: A total of 174 eyes of patients with neovascular age-related macular degeneration who had not received previous treatment were included in the study. Visual acuity, neovascularization activity, and the appearance or not of the different signs understudy were assessed at times 0 (initial visit), 4 months, one year, year and a half, and at 2 and 3 years of follow-up. The following were also evaluated: age, sex, affected eye and type of neovascularization (1, 2, 3, polypoid or mixed). The analysis were performed using the statistical software R (version 3.3.2) and the glmmADMB package (version 0.8.3.3). RESULTS: The presence of pseudocysts and external retinal tubulation increases throughout the follow-up. The onion sign begins with an ascending frequency up to 12 months, then decreases at 18 months and increases again at 24 months. Regarding pseudowelling, it maintains an increase until 18 months to finally decrease. Subretinal clefts is the rarest sign, presenting in 1.1% on the first visit. Finally, macular atrophy, present in 12.6% of the eyes initially, is found in 25% after 2 years. CONCLUSION: Pseudocysts, external retinal tubulation and macular atrophy were the most prevalent signs, while subretinal clefts were the most infrequent.
PB Elsevier
SN 0365-6691
YR 2023
FD 2023-05
LK https://uvadoc.uva.es/handle/10324/68990
UL https://uvadoc.uva.es/handle/10324/68990
LA spa
NO Arch Soc Esp Oftalmol (Engl Ed), May 2023, vol. 98, n. 5, p. 276-280.
NO Producción Científica
DS UVaDOC
RD 01-ago-2024