RT info:eu-repo/semantics/article T1 Effects of immunonutrition on cancer patients undergoing surgery: a scoping review A1 García Malpartida, Katherine A1 Aragón Valera, Carmen A1 Botella Romero, Francisco A1 Ocón Bretón, María Julia A1 López Gómez, Juan José K1 Cancer - Surgery K1 Cáncer - Cirugía K1 Oncology K1 Surgical oncology K1 Cirurgia oncològica K1 Immunonutrition K1 Nutrition K1 Food science K1 Cancer K1 Cancer - Complications K1 Cáncer - Complicaciones y secuelas K1 Mortality K1 Mortalidad K1 Immunology K1 3207.13 Oncología K1 3213 Cirugía K1 3206 Ciencias de la Nutrición K1 2412 Inmunología AB Introduction: There is a large body of evidence about immunonutrition formulas; however, there are still doubts about their usefulness in routine clinical practice as compared with standard formulas. In the age of personalized medicine, new studies appear every year regarding several types of patients; therefore, an updated point of view on these formulas is necessary. Methods: The Embase database was searched from 2016 to 14 March 2022. Our criteria were articles published in English and Spanish. The evidence quality was evaluated using GRADEpro, and the review was developed according to the PRISMA statement. Results: In this review, a total of 65 unique records were retrieved; however, 36 articles did not meet the inclusion criteria and were thus excluded. In total, 29 articles were included in the final analysis. In the last few years, many meta-analyses have attempted to identify additional existing studies of surgical patients with certain pathologies, mainly oncological patients. Immunonutrition prior to oncological surgery was shown to cause a decrease in inflammatory markers in most of the studies, and the main clinical events that changed were the infectious complications after surgery. The length of stay and mortality data are controversial due to the specific risk factors associated with these events. Conclusions: The use of immunonutrition in patients who have undergone oncological surgery decreases the levels of inflammatory markers and infectious postoperative complications in almost all localizations. However, more studies are needed to assess the use of immunonutrition based on Enhanced Recovery After Surgery (ERAS) protocols. PB MDPI SN 2072-6643 YR 2023 FD 2023 LK https://uvadoc.uva.es/handle/10324/69111 UL https://uvadoc.uva.es/handle/10324/69111 LA eng NO Nutrients, 2023, Vol. 15, Nº. 7, 1776 NO Producción Científica DS UVaDOC RD 06-oct-2024