RT info:eu-repo/semantics/article
T1 Modified sequential organ failure assessment score vs. early warning scores in prehospital care to predict major adverse cardiac events in acute cardiovascular disease
A1 Castro Portillo, Enrique
A1 López Izquierdo, Raúl
A1 Castro Villamor, Miguel Ángel
A1 Sanz García, Ancor
A1 Martín Conty, José Luis
A1 Polonio López, Begoña
A1 Sánchez Soberón, Irene
A1 Pozo Vegas, Carlos del
A1 Durántez Fernández, Carlos
A1 Conty Serrano, Rosa
A1 Martín Rodríguez, Francisco
K1 Cardiovascular system - Diseases
K1 Cardiovascular, Aparato - Enfermedades
K1 Cardiovascular Diseases
K1 Enfermedad cardiovascular
K1 Biomarkers
K1 Early warning system
K1 Emergency medical services
K1 Medicina de urgencias
K1 Atención prehospitalaria
K1 Mortality
K1 Mortalidad
K1 Medicine
K1 Cardiology
K1 Public health
K1 32 Ciencias Médicas
K1 3205.01 Cardiología
K1 3207.04 Patología Cardiovascular
K1 3212 Salud Publica
AB (1) Background: The Modified Sequential Organ Failure Assessment (mSOFA) is an Early Warning Score (EWS) that has proven to be useful in identifying patients at high risk of mortality in prehospital care. The main objective of this study was to evaluate the predictive validity of prehospital mSOFA in estimating 2- and 90-day mortality (all-cause) in patients with acute cardiovascular diseases (ACVD), and to compare this validity to that of four other widely-used EWS. (2) Methods: We conducted a prospective, observational, multicentric, ambulance-based study in adults with suspected ACVD who were transferred by ambulance to Emergency Departments (ED). The primary outcome was 2- and 90-day mortality (all-cause in- and out-hospital). The discriminative power of the predictive variable was assessed and evaluated by the area under the curve (AUC) of the receiver operating characteristic (ROC). (3) Results: A total of 1540 patients met the inclusion criteria. The 2- and 90-day mortality rates were 5.3% and 12.7%, respectively. The mSOFA showed the highest AUC of all the evaluated scores for both 2- and 90-day mortality, AUC = 0.943 (0.917–0.968) and AUC = 0.874 (0.847–0.902), respectively. (4) Conclusions: The mSOFA is a quick and easy-to-use EWS with an excellent ability to predict mortality at both 2 and 90 days in patients treated for ACVD, and has proved to be superior to the other EWS evaluated in this study.
PB MDPI
SN 2308-3425
YR 2023
FD 2023
LK https://uvadoc.uva.es/handle/10324/69385
UL https://uvadoc.uva.es/handle/10324/69385
LA eng
NO Journal of Cardiovascular Development and Disease, 2023, Vol. 10, Nº. 2, 88
NO Producción Científica
DS UVaDOC
RD 22-dic-2024