RT info:eu-repo/semantics/article T1 Endoscopic gallbladder drainage: a comprehensive review on indications, techniques, and future perspectives A1 Troncone, Edoardo A1 Amendola, Rosa A1 Moscardelli, Alessandro A1 De Cristofaro, Elena A1 De Vico, Pasquale A1 Paoluzi, Omero Alessandro A1 Monteleone, Giovanni A1 Pérez-Miranda Castillo, Manuel A1 Del Vecchio Blanco, Giovanna K1 Acute cholecystitis K1 Colecistitis - Tratamiento K1 Gallbladder - Diseases K1 Vésicula biliar - Enfermedades K1 Gastroenterology K1 Endoscopic ultrasonography K1 Ultrasonidos en medicina K1 Endoscopic retrograde cholangiopancreatography K1 Drainage, Surgical K1 Gastrointestinal system - Diseases K1 Sistema gastrointestinal - Enfermedades K1 Medicine K1 3205.03 Gastroenterología K1 32 Ciencias Médicas AB In recent years, therapeutic endoscopy has become a fundamental tool in the management of gallbladder diseases in light of its minimal invasiveness, high clinical efficacy, and good safety profile. Both endoscopic transpapillary gallbladder drainage (TGBD) and endoscopic ultrasound (EUS)-guided gallbladder drainage (EUS-GBD) provide effective internal drainage in patients with acute cholecystitis unfit for cholecystectomy, avoiding the drawbacks of external percutaneous gallbladder drainage (PGBD). The availability of dedicated lumen-apposing metal stents (LAMS) for EUS-guided transluminal interventions contributed to the expansion of endoscopic therapies for acute cholecystitis, making endoscopic gallbladder drainage easier, faster, and hence more widely available. Moreover, EUS-GBD with LAMS opened the possibility of several cholecystoscopy-guided interventions, such as gallstone lithotripsy and clearance. Finally, EUS-GBD has also been proposed as a rescue drainage modality in malignant biliary obstruction after failure of standard techniques, with encouraging results. In this review, we will describe the TBGD and EUS-GBD techniques, and we will discuss the available data on clinical efficacy in different settings in comparison with PGBD. Finally, we will comment on the future perspectives of EUS-GBD, discussing the areas of uncertainty in which new data are more strongly awaited. PB MDPI SN 1648-9144 YR 2024 FD 2024 LK https://uvadoc.uva.es/handle/10324/70098 UL https://uvadoc.uva.es/handle/10324/70098 LA eng NO Medicina, 2024, Vol. 60, Nº. 4, 633 NO Producción Científica DS UVaDOC RD 08-ene-2025