RT info:eu-repo/semantics/article
T1 Skeletal muscle signaling response to sprint exercise in men and women
A1 Fuentes, Teresa
A1 Guerra, Borja
A1 Ponce-González, Jesús G.
A1 Morales-Alamo, David
A1 Guadalupe-Grau, Amelia
A1 Olmedillas, Hugo
A1 Rodríguez-García, Lorena
A1 Feijoo, David
A1 De Pablos-Velasco, Pedro
A1 Fernández-Pérez, Leandro
A1 Santana, Alfredo
A1 Calbet, Jose A. L.
AB To determine if there is a sex dimorphism in the skeletal muscle signaling response to sprint exercise, 17 men and ten women performed a 30-s Wingate test. Muscle biopsies were taken before, immediately after the exercise and at 30 and 120 min during the recovery period. Thr(172)-AMPKα, Ser(221)-ACCβ, Thy(705)-STAT3, Thr(202)/Thy(204)-ERK1/2 and Thr(180)/Thy(182)-p38MAPK phosphorylation responses to sprint exercise were not statistically different between men and women. AMPKα phosphorylation was enhanced fourfold 30 min after the sprint exercise in males and females (P < 0.01). ACCβ phosphorylation was enhanced by about threefold just after the sprint test exercise and 30 min into the recovery period in males and females (P < 0.01). STAT3 phosphorylation was increased 2 h after the Wingate test compared to the value observed right after the end of the exercise (P < 0.05), and 30 min after the Wingate test there was a 2.5-fold increase in ERK1/2 phosphorylation, compared to both the pre-exercise and to the value observed right after the Wingate test (both, P < 0.05). In conclusion, the skeletal muscle signaling response to a single bout of sprint exercise mediated by AMPK, ACC, STAT3, ERK and p38MAPK is not statistically different between men and women. Marked increases in AMPKα, ACCβ, STAT3 and ERK phosphorylation were observed after a single 30-s all-out sprint (Wingate test) in the vastus lateralis.
SN 1439-6319
YR 2011
FD 2011
LK https://uvadoc.uva.es/handle/10324/72609
UL https://uvadoc.uva.es/handle/10324/72609
LA eng
NO 8.	Fuentes, T., Guerra, B., Ponce-González, J.G., Morales‐Alamo, D., Guadalupe-Grau, A., Olmedillas, H., Rodríguez-García, L., Feijoo, D., Pablos-Velasco, P.D., Fernández-Pérez, L., Santana, A., & Calbet, J.A. (2011). Skeletal muscle signaling response to sprint exercise in men and women. European Journal of Applied Physiology, 112, 1917 - 1927.
NO Producción Científica
DS UVaDOC
RD 20-dic-2024