RT info:eu-repo/semantics/article
T1 Assocation between trapezium size and failure of total trapeziometacarpal prosthesis. A survival analysis
A1 Simón Pérez, Clarisa
A1 Martín Ferrero, Miguel Ángel
A1 Hernández Cortés, Pedro
A1 Coco Martín, María Begoña
A1 Rosales, Roberto S.
AB Aims: To assess the survival function of cementless total trapezium metacarpalprostheses (TTMPs) at 20 years, to compare survival functions by trapezium size, andto evaluate the association between the instantaneous risk of TTMP failure and smalltrapezium size using a multivariate Cox regression model.Methods: This observational cohort study included 221 consecutive patients with amean follow-up after TTMP of 138.1 months (maximum of 246 months). Kaplan-Meierand actuarial life-table methods were used to evaluate the survival function of thecohort. Kaplan-Meier survival curves were compared by trapezium size. MultivariateCox regression analysis was used to determine the effect of potential confounders onthe association between small trapezium and the instantaneous risk of TTMP failure.Results:At the end of follow-up, there was a 89.01% chance of the TTMP surviving for 246months or more. There was an association between TTMP survival time andtrapezium size showing a significant trend such that the survival curves weresignificantly higher with larger trapezium size (Mantel-Cox test, p = 0.0001; Wilcoxon-Breslow test, p = 0.0002; Tarone-Ware test, p = 0.0001).The unadjusted Coxregression model showed a significant association between small trapezium size(smaller than 9 mm) and the instantaneous risk of TTPM failure (HR: 7.37, 95% CI:2.46-22.07). In the multivariate Cox analysis, "age", "trapezium morphology", and"complications" were confounders in the association between small trapezium size andthe hazard ratio of prosthetic failure (HR = 3.76; 95% CI 0.96 to 13.82).Conclusions: These results confirm the long-term functional survival of TTMPprostheses and reveal a significant increase in trend of the survival curve with largertrapezium size. Patient age, trapezium morphology, and the presence of post-surgicalcomplications are confounders in the association between small trapezium size andthe hazard ratio of TTMP failure.
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/72850
UL https://uvadoc.uva.es/handle/10324/72850
LA spa
NO Archives of Orthopaedic and Trauma Surgery, septiembre 2024, vol. 144, p. 4275–4282
DS UVaDOC
RD 24-abr-2025