RT info:eu-repo/semantics/article T1 Persistent ischiorectal fistula secondary to rectal extrusion of posterior vaginal mesh: case report A1 Miguel Manso, María Sonia de A1 Andrés Asenjo, Beatriz de A1 Gobernador Tejedor, Julio A1 García García, Elena A1 Vázquez Fernández, Andrea A1 Álvarez Colomo, Cristina K1 Ischiorectal fistula K1 Platelet-rich plasma K1 Posterior vaginal mesh K1 Rectal extrusion AB Introduction and hypothesis: Vaginal mesh has been used for years to try to improve the results of pelvic organ prolapse surgery, but current evidence does not confirm this improvement and instead describes serious and frequent adverse events.Clinical case: 64-year-old patient with rectal extrusion of posterior vaginal mesh placed 8 years earlier, and persistent left ischiorectal fistula refractory to surgery.She required 5 surgeries, carried out jointly between gynecology and general surgery, to solve, firstly, the bilateral perianal abscess secondary to extrusion of the posterior vaginal mesh into the rectum and then the persistent left ischiorectal fistula, despite the removal of the material prosthetic. Finally, the fistula was solved by injection of platelet-rich plasma.Conclusions: Vaginal mesh complications often need a multidisciplinary approach, and treatment may require multiple approaches and more than one surgical procedure.In the case of a persistent fistula refractory to surgery, after removing the mesh, non-invasive regenerative therapies that promote vascular growth and tissue regeneration could be considered such as platelet-rich plasma. PB Elsevier SN 0301-2115 YR 2024 FD 2024 LK https://uvadoc.uva.es/handle/10324/72955 UL https://uvadoc.uva.es/handle/10324/72955 LA eng NO European Journal of Obstetrics & Gynecology and Reproductive Biology, 2024, vol. 299, p. 173-181 NO Producción Científica DS UVaDOC RD 22-dic-2024