RT info:eu-repo/semantics/article
T1 Development and validation of an analytical methodology based on solvent microextraction and UHPLC-MS/MS for determining bisphenols in honeys from different botanical origins
A1 Martín Gómez, Beatriz
A1 Valverde Bastardo, Silvia
A1 Bernal del Nozal, José
A1 Ares Sacristán, Ana María
K1 Bisphenols
K1 Food safety
K1 Green analytical chemistry
K1 Honey
K1 UHPLC-MS/MS
K1 Method validation
K1 Sample treatment
AB A new analytical methodology was proposed to determine fourteen bisphenols in honeys from different botanical origins using ultra-high performance liquid chromatography-tandem mass spectrometry. A fast, efficient, environmentally-friendly and simple sample treatment (recoveries between 81% and 116%; matrix effect <20% for all studied compounds except for bisphenol E, F and S) was proposed, which involved a solvent microextraction with acetone and a small volume/amount of 1-hexanol. Chromatographic analysis (< 15 min) was performed in a Kinetex EVO C18 column under gradient elution mode. The method was validated in terms of selectivity, limits of detection (0.2–1.5 μg/kg) and quantification (0.5–4.7 μg/kg), linearity, matrix effect, trueness, and precision (relative standard deviation <17%). Finally, thirty honey samples were analyzed, revealing the presence of residues of nine bisphenols in some of them. However, quantification was possible only in two cases for bisphenol A, with a concentration of approximately 13 μg/kg.
PB Elsevier
SN 0308-8146
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/72958
UL https://uvadoc.uva.es/handle/10324/72958
LA eng
NO Food Chemistry, 2024, vol. 450, 139358
NO Producción Científica
DS UVaDOC
RD 22-dic-2024