RT info:eu-repo/semantics/article T1 A systematic review of the socioeconomic impact of mechanical thrombectomy for acute ischemic stroke A1 Martín Gutiérrez, Adrián A1 Leal Vega, Luis A1 Coco Martín, María Begoña A1 Arenillas Lara, Juan Francisco K1 Ischemic stroke K1 Mechanical thrombectomy K1 Socioeconomic impact K1 Systematic review K1 32 Ciencias Médicas AB Background: Mechanical Thrombectomy (MT) is an efficacious treatment for severe acute ischemic stroke patients. However, access to MT is limited in many parts of the world, partly due to economic barriers. The purpose of this systematic review is to provide an updated frame about the socioeconomic impact of MT.Methods: To carry out this systematic review we used the PRISMA guidelines. We included scientific articles analyzing the socioeconomic impact of MT for acute ischemic stroke, in which MT was compared to best medical therapy (BMT). The online databases of Pubmed, Scopus and Web of Science were used as main sources of information. To carry out the comparative analysis, the incremental cost-effectiveness ratio (ICER) was used, relating the cost to quality-adjusted life-year (QALY). Risk of bias was assessed with the Consensus Health Economic Criteria (CHEC) and the Consolidated Health Economic Evaluation Reporting Standards (CHEERS).Results: Eight hundred thirty-two studies were identified in this systematic review. As a result, studies that used cost-effectiveness analysis show that MT saves costs in the long term and cost-utility analysis show that the cost per QALY is reasonable with a mean ICER value of $14242.36/QALY.Conclusions: MT has a favorable socioeconomic impact, as derived from cost-effectiveness and cost-utility analyses. Therefore, public policies should encourage the implementation of MT for stroke patients around the world. PB Elsevier SN 1052-3057 YR 2024 FD 2024 LK https://uvadoc.uva.es/handle/10324/73290 UL https://uvadoc.uva.es/handle/10324/73290 LA eng NO Journal of Stroke and Cerebrovascular Diseases, noviembre 2024, vol. 33, n. 11, 10790 NO Producción Científica DS UVaDOC RD 10-ene-2025