RT info:eu-repo/semantics/article
T1 Effectiveness of high-protein energy-dense oral supplements on patients with malnutrition using morphofunctional assessment with AI-assisted muscle ultrasonography: A real-world one-arm study
A1 López Gómez, Juan José
A1 Primo Martín, David
A1 Cebria, Ángela
A1 Izaola Jauregui, Olatz
A1 Godoy, Eduardo Jorge
A1 Pérez López, Paloma
A1 Jiménez Sahagún, Rebeca
A1 Ramos Bachiller, Beatriz
A1 González Gutiérrez, Jaime
A1 Luis Román, Daniel Antonio de
AB Background: User-friendly tools for assessing nutrition status and interventions in malnourishedpatients are crucial. This study evaluated the effectiveness of a personalised nutritionintervention using a novel oral nutritional supplement and AI-supported morphofunctional assessmentto monitor clinical outcomes in patients with disease-related malnutrition (DRM). Methods: Thisprospective observational study involved patients receiving concentrated high-protein, high-calorieONS (cHPHC-ONS), per usual clinical practice. Comprehensive assessments were performed atbaseline (B0) and three months (M3) post-intervention. Results: 65 patients participated in the study.Significant decreases were observed in the percentage weight loss from B0 (−6.75 ± 7.5%) to M3(0.5 ± 3.48%) (p < 0.01), in the prevalence of malnutrition (B0: 93.4%; M3: 78.9%; p < 0.01), severemalnutrition (B0: 60.7%; M3: 40.3%; p < 0.01), and sarcopenia (B0: 19.4%; M3: 15.5%; p < 0.04).Muscle area increased (p = 0.03), and there were changes in the echogenicity of the rectus femorismuscle (p = 0.03) from B0 to M3. In patients aged ≥60, an increase in muscle thickness (p = 0.04),pennation angle (p = 0.02), and handgrip strength (p = 0.04) was observed. There was a significantreduction in the prevalence of malnutrition (B0: 93.4%; M3: 78.9%; p < 0.01) and severe malnutrition(B0: 60.7%; M3: 40.3%; p < 0.01). Conclusions: In patients with DRM, a personalised interventionwith cHPHC-ONS significantly reduces the prevalence of malnutrition, severe malnutrition, andsarcopenia and improves muscle mass and function.
PB MDPI
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/73687
UL https://uvadoc.uva.es/handle/10324/73687
LA eng
NO Nutrients, 2024, vol. 16, 3136.
NO Producción Científica
DS UVaDOC
RD 09-abr-2025