RT info:eu-repo/semantics/article
T1 Ultrasound Cut-Off Values for Rectus Femoris for Detecting Sarcopenia in Patients with Nutritional Risk
A1 de luis roman, Daniel
AB Background: A nationwide, prospective, multicenter, cohort study (the Disease-Relatedcaloric-protein malnutrition EChOgraphy (DRECO) study) was designed to assess the usefulness ofultrasound of the rectus femoris for detecting sarcopenia in hospitalized patients at risk of malnutritionand to define cut-off values of ultrasound measures. Methods: Patients at risk of malnutritionaccording to the Malnutrition Universal Screening Tool (MUST) underwent handgrip dynamometry,bioelectrical impedance analysis (BIA), a Timed Up and Go (TUG) test, and rectus femoris ultrasoundstudies. European Working Group on Sarcopenia in Older People (EWGSOP2) criteriawere used to define categories of sarcopenia (at risk, probable, confirmed, severe). Receiver operatingcharacteristic (ROC) and area under the curve (AUC) analyses were used to determine the optimaldiagnostic sensitivity, specificity, and predictive values of cut-off points of the ultrasoundmeasures for the detection of risk of sarcopenia and probable, confirmed, and severe sarcopenia.Results: A total of 1000 subjects were included and 991 of them (58.9% men, mean age 58.5 years)were evaluated. Risk of sarcopenia was detected in 9.6% patients, probable sarcopenia in 14%, confirmedsarcopenia in 9.7%, and severe sarcopenia in 3.9%, with significant differences in the distributionof groups between men and women (p < 0.0001). The cross-sectional area (CSA) of the rectusfemoris showed a significantly positive correlation with body cell mass of BIA and handgripstrength, and a significant negative correlation with TUG. Cut-off values were similar within eachcategory of sarcopenia, ranging between 2.40 cm2 and 3.66 cm2 for CSA, 32.57 mm and 40.21 mm forthe X-axis, and 7.85 mm and 10.4 mm for the Y-axis. In general, these cut-off values showed high
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/73692
UL https://uvadoc.uva.es/handle/10324/73692
LA eng
NO Nutrients 2024, 16, 1552.
DS UVaDOC
RD 31-ene-2025