RT info:eu-repo/semantics/article T1 Ultrasound cut-off values for rectus femoris for detecting sarcopenia in patients with nutritional risk A1 Luis Román, Daniel Antonio de A1 García Almeida, José Manuel A1 Bellido Guerrero, Diego A1 Guzmán Rolo, Germán A1 Martín, Andrea A1 Primo Martín, David A1 García Delgado, Yaiza A1 Guirado Peláez, Patricia A1 Palmas, Fiorella A1 Tejera Pérez, Cristina A1 García Olivares, María A1 Maíz Jiménez, María A1 Bretón Lesmes, Irene A1 Alzás Teomiro, Carlos Manuel A1 Guardia Baena, Juan Manuel A1 Calles Romero, Laura A. A1 Prior Sánchez, Inmaculada A1 García Luna, Pedro Pablo A1 González Pacheco, María A1 Martínez Olmos, Miguel Ángel A1 Alabadí, Blanca A1 Alcántara Aragón, Valeria A1 Palma Milla, Samara A1 Martín Folgueras, Tomás A1 Micó García, Andrea A1 Molina Baena, Begoña A1 Rendón Barragán, Henry A1 Rodríguez de Vera Gómez, Pablo A1 Riestra Fernández, María A1 Jiménez Portilla, Ana A1 López Gómez, Juan José A1 Pérez Martín, Nuria A1 Montero Madrid, Natalia A1 Zabalegui Eguinoa, Alba A1 Porca Fernández, Cristina A1 Tapia Guerrero, María José A1 Ruiz Aguado, Marta A1 Velasco Gimeno, Cristina A1 Herrera Martínez, Aura D A1 Novo Rodríguez, María A1 Iglesias Hernández, Natalia C. A1 Damas Medina, María de A1 González Navarro, Irene A1 Vílchez López, Francisco Javier A1 Fernández Pombo, Antía A1 Olveira, Gabriel K1 sarcopenia K1 nutritional ultrasound K1 ultrasound cut-off values K1 rectus femoris K1 malnutrition K1 nutritional risk AB Background: A nationwide, prospective, multicenter, cohort study (the Disease-Relatedcaloric-protein malnutrition EChOgraphy (DRECO) study) was designed to assess the usefulness ofultrasound of the rectus femoris for detecting sarcopenia in hospitalized patients at risk of malnutritionand to define cut-off values of ultrasound measures. Methods: Patients at risk of malnutritionaccording to the Malnutrition Universal Screening Tool (MUST) underwent handgrip dynamometry,bioelectrical impedance analysis (BIA), a Timed Up and Go (TUG) test, and rectus femoris ultrasoundstudies. European Working Group on Sarcopenia in Older People (EWGSOP2) criteriawere used to define categories of sarcopenia (at risk, probable, confirmed, severe). Receiver operatingcharacteristic (ROC) and area under the curve (AUC) analyses were used to determine the optimaldiagnostic sensitivity, specificity, and predictive values of cut-off points of the ultrasoundmeasures for the detection of risk of sarcopenia and probable, confirmed, and severe sarcopenia.Results: A total of 1000 subjects were included and 991 of them (58.9% men, mean age 58.5 years)were evaluated. Risk of sarcopenia was detected in 9.6% patients, probable sarcopenia in 14%, confirmedsarcopenia in 9.7%, and severe sarcopenia in 3.9%, with significant differences in the distributionof groups between men and women (p < 0.0001). The cross-sectional area (CSA) of the rectusfemoris showed a significantly positive correlation with body cell mass of BIA and handgripstrength, and a significant negative correlation with TUG. Cut-off values were similar within eachcategory of sarcopenia, ranging between 2.40 cm2 and 3.66 cm2 for CSA, 32.57 mm and 40.21 mm forthe X-axis, and 7.85 mm and 10.4 mm for the Y-axis. In general, these cut-off values showed high PB MDPI YR 2024 FD 2024 LK https://uvadoc.uva.es/handle/10324/73692 UL https://uvadoc.uva.es/handle/10324/73692 LA eng NO Nutrients, 2024, vol. 16, n. 11, 1552. NO Producción Científica DS UVaDOC RD 25-abr-2025