RT info:eu-repo/semantics/article
T1 Management of disease-related malnutrition: a real-world experience with a novel concentrated high-protein energy-dense oral nutritional supplement
A1 López-Gómez, Juan J.
A1 Bachiller, Beatriz Ramos
A1 de Luis Roman, Daniel
A1 De Luis
AB Objective: Despite the availability of a wide range of oral nutritional supplements (ONS) offerings,individuals with malnutrition are still struggling to meet their nutritional targets. A new concentratedand high-protein energy-dense ONS (≥2.1 kcal/mL;32 g protein/200 mL) with high-quality protein (60%whey protein) has emerged as a pivotal formula to reach the patient’s energy-protein requirements,enhance compliance, and maximize stimulation of muscle protein synthesis, key factors driving betternutritional, functional, and clinical outcomes. The purpose of this article is to provide our clinicalexperience using this new nutritionally concentrated ONS as a therapeutic strategy for patients withDRM.Methods: Three clinical cases have been examined using new assessment procedures and a new formof nutritional therapy, and their impact on the nutritional and functional outcomes in patients withmoderate-to-severe DRM.Results: A tailored individualized nutritional interventions improved anthropometric, biochemical, andfunctional outcomes (Case 1,2, and 3) assessed using hand grip strength, bioimpedance and muscleultrasound, and as well as good gastrointestinal tolerance (Case 1) and compliance to the ONS inpatients with DRM (Case 1,2,3).Conclusion: The use of this novel high-protein energy-dense formula with high-quality protein source(≥2.1 kcal/mL; 32 g protein/200 mL; 60% whey protein) overcome common practical challenges in themedical nutrition therapy of patients with DRM, either because these patients require a highly concentratedformulation to meet nutritional requirements due to loss of appetite, lack of interest in food,and high caloric-protein needs due to disease, and a large quantity and quality of protein to optimizemuscle recovery due to sarcopenia, common in patients with moderate-severe malnutrition.
SN 0032-5481
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/73695
UL https://uvadoc.uva.es/handle/10324/73695
LA spa
NO López-Gómez JJ, Bachiller BR, de Luis Roman D. Management of disease-related malnutrition: a real-world experience with a novel concentrated high-protein energy-dense oral nutritional supplement. Postgrad Med. 2024 Jan;136(1):52-59. doi: 10.1080/00325481.2024.2307869. Epub 2024 Jan 25. PMID: 38251982.
DS UVaDOC
RD 31-ene-2025