RT info:eu-repo/semantics/article T1 Clostridia as Promising Biofactory for Heterotrophic (Fructose) and Autotrophic (C1-Gas) Fermentation A1 Fernández Delgado, Marina A1 Coca Sanz, Mónica A1 Lucas Yagüe, Susana A1 García Cubero, María Teresa A1 López Linares, Juan Carlos K1 3302.90 Ingeniería Bioquímica AB This study compared the performance of Clostridium ljungdahlii and Clostridium aceticum in the fermentation of fructose and C1-gasses (CO, CO2, N2) to produce valuable products such as ethanol and acetic acid. In heterotrophic fermentation (fructose), C. ljungdahlii yielded high ethanol concentrations (350 mg/L) and acetic acid (500 mg/L), with optimal production at pH 8 on the first day of fermentation. Although autotrophic fermentation (C1-gasses) resulted in lower ethanol levels (200 mg/L), it remained a viable option. Conversely, C. aceticum predominantly produced acetic acid in both fermentation modes, with higher concentrations in the heterotrophic fermentation (1600 mg/L) than the autotrophic fermentation (380 mg/L). These findings demonstrate the versatility of both microorganisms for producing valuable metabolites. C. ljungdahlii shows promise for bioethanol production, while C. aceticum excels at generating acetic acid, a crucial component in bioplastics and various industrial processes. PB MDPI SN 2311-5637 YR 2024 FD 2024 LK https://uvadoc.uva.es/handle/10324/73779 UL https://uvadoc.uva.es/handle/10324/73779 LA eng NO Fermentation 2024, 10(11), 572 NO Producción Científica DS UVaDOC RD 22-ene-2025