RT info:eu-repo/semantics/article T1 Quantification of myosin heavy chain isoform mRNA transcripts in the supraspinatus muscle of vertical clinger primates A1 Potau, Josep Maria A1 Artells, Rosa A1 Muñoz, Carmen A1 Arias Martorell, Júlia A1 Bello Hellegouarch, Gaëlle A1 Pérez Pérez, Alejandro A1 Barbosa Cachorro, María Mercedes A1 Pastor Vázquez, Juan Francisco A1 Paz Fernández, Félix Jesús de K1 Primates hominoideos K1 Músculos K1 Myosin heavy chain K1 Supraspinatus K1 Vertical clinging K1 2401.01 Anatomía Animal AB Vertical clinging is a specialized form of locomotion characteristic of the primate family Callitrichidae. Vertical clinging requires these pronograde primates to maintain a vertical posture, so the protraction of their forelimbs must resist gravity. Since pronograde primates usually move as horizontal quadrupeds, we hypothesized that the supraspinatus muscle of vertical clingers would present specific characteristics related to the functional requirements imposed on the shoulder area by vertical clinging. To test thishypothesis, we quantified by real-time quantitative polymerase chain reaction the mRNAtranscripts of myosin heavy chain (MHC) isoforms in the supraspinatus muscle of 15 speciesof pronograde primates, including vertical clingers. Our results indicate that the supraspinatusof vertical clingers has a specific expression pattern of the MHC isoforms, with a low expression of the transcripts of the slow MHC-I isoform and a high expression of the transcripts of the fast MHC-II isoforms. We conclude that these differences can be related to the particular functional characteristics of the shoulder in vertical clingers, but also to other anatomical adaptations of these primates, such as their small body size. PB BRILL SN 0015-5713 YR 2017 FD 2017 LK https://uvadoc.uva.es/handle/10324/74324 UL https://uvadoc.uva.es/handle/10324/74324 LA eng NO Folia Primatologica, Abril 2017, n. 88. p. 497-506. NO Producción Científica DS UVaDOC RD 22-abr-2025