RT info:eu-repo/semantics/article
T1 Development and validation of ultra high performance-liquid-chromatography-tandem mass spectrometry-based methods for the determination of neonicotinoid insecticides in honey
A1 Valverde Bastardo, Silvia
A1 Ibáñez, María
A1 Bernal Yagüe, José Luis
A1 Nozal Nalda, María Jesús del
A1 Hernández, Félix
A1 Bernal del Nozal, José
K1 mass spectrometry, honey, development, neonicotinoid
AB In this study, the feasibility of two sample treatments has been evaluated for the determination of seven neonicotinoid insecticides in honey from different botanical origins using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS). A solid phase extraction with a polymeric sorbent (Strata® X) is proposed for analyzing dark honeys, while a QuEChERS (quick, easy, cheap, effective, rugged and safe) approach is recommended for light honeys. Chromatographic analysis (6 min) was performed on a core-shell column (Kinetex® EVO C18). The proposed methods were fully validated using two different MS/MS systems: quadrupole-time-of-flight and triple quadrupole. The results showed that the best overall analytical performance was achieved using triple quadrupole, mainly due to its better sensitivity and the reduced influence of the matrix onto the analyte signals. The methods developed were applied to the analysis of commercial honey samples from different regions of Spain, as well as from experimental apiaries.
PB Elsevier
YR 2018
FD 2018
LK https://uvadoc.uva.es/handle/10324/74560
UL https://uvadoc.uva.es/handle/10324/74560
LA eng
NO Food Chemistry, 2018, vol. 266, p. 215-222.
DS UVaDOC
RD 09-mar-2025