RT info:eu-repo/semantics/bookPart T1 Chemical modification of biomaterials from nature A1 Rodríguez Cabello, José Carlos A1 González de Torre, Israel A1 Santos García, María Mercedes A1 Testera Gorgojo, Ana María A1 Alonso Rodrigo, Matilde K1 23 Química K1 32 Ciencias Médicas AB Protein modification is an area of an intense research and many methods have been developed with applications in fields including biology, chemistry and medicine, as they are powerful tools for studying protein expression and localization, and engineering the functions of protein both in vitro and in live cells or in vivo to create new biocatalysts and bioanalytical tools. There are different high precision protein modification methods which can be roughly divided into two categories. The first involve the use of a genetic modification system and the second is based on the labeling of expressed proteins taking advantages of the chemical reactivity of the amino acid side chains. As they occur after the protein biosynthesis step, these chemical modifications, are commonly referred to as post-translational modifications (PTMs). Natural polysaccharides and their derivatives are emerging polymers in pharmaceutical and biomedical fields such as tissue engineering, particularly for cartilage, drug delivery devices and gel-entrapment systems for cells immobilization. PB Wiley SN 9781118478059 YR 2016 FD 2016 LK https://uvadoc.uva.es/handle/10324/74850 UL https://uvadoc.uva.es/handle/10324/74850 LA eng NO Neves, Nuno M. y Reis, Rui L. (eds.). Biomaterials from nature for advanced devices and therapies. Hoboken (New Jersey): John Wiley & Sons, 2016, p. 444-474 NO Producción Científica DS UVaDOC RD 16-abr-2025