RT info:eu-repo/semantics/article
T1 Insight into the key factors that influence the reaction pathways in the silyl‐Prins cyclization of gem‐vinylsilyl alcohols
A1 González Andrés, Paula
A1 Díez Poza, Carlos
A1 Fernández Peña, Laura
A1 González Pinardo, Daniel
A1 Fernández, Israel
A1 Barbero Pérez, María Asunción
K1 Prins cyclization
K1 organosilanes
K1 computational studies
K1 Lewis acids
K1 Stereocontrol
K1 2306 Química Orgánica
AB This work provides an in-depth analysis of the factors governing the different reaction pathways in the acid-catalyzed cyclization of gem-vinylsilyl alcohols with aldehydes. The study evaluates the impact of both the ligands attached to silicon and the choice of the Lewis acid on the reaction outcome. Additionally, computational studies offer valuable insights into the mechanism that control these distinct pathways. The process enables the chemo- and stereocontrolled formation of a variety of structural frameworks, offering significant potential for the generation of a broad range of molecular architectures.
PB Wiley
SN 1615-4150
YR 2025
FD 2025
LK https://uvadoc.uva.es/handle/10324/75144
UL https://uvadoc.uva.es/handle/10324/75144
LA eng
NO Advances Synthesis & Catalysis, [Early view]
NO Producción Científica
DS UVaDOC
RD 09-mar-2025