RT info:eu-repo/semantics/article
T1 Supercritical fluid chromatography in bioanalysis–A review
A1 Toribio Recio, Laura
A1 Martín Gómez, María Teresa
A1 Bernal del Nozal, José
K1 doping analysis
K1 forensic analysis
K1 lipidomics
K1 Metabolomics
K1 2301 Química Analítica
AB In the last decade, the instrumentation improvements in supercritical fluid chromatography (SFC) and the hyphenation to mass spectrometry (MS), have increased the SFC acceptance between scientists, becoming today a valuable tool in analytical chemistry. The unique selectivity, short analysis times, low consumption of organic solvents, and the greener mobile phase, have contributed to expanding its applicability which has led to an increase in the number of publications especially in the bioanalysis area. This work reviews the advantages and main applications of SFC in bioanalysis during the last 5 years. Fundamental aspects concerning mobile phase composition, stationary phase, hyphenation to MS as well as matrix effect have been discussed. Finally, the most relevant applications have been summarized.
PB Wiley
SN 1615-9306
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/75157
UL https://uvadoc.uva.es/handle/10324/75157
LA eng
NO Journal of Separation Science, 2024, vol. 47, n. 21, e70003
NO Producción Científica
DS UVaDOC
RD 09-mar-2025