RT info:eu-repo/semantics/article
T1 Stereoselective synthesis of polysubstituted tetrahydropyrans by Brønsted acid‐mediated hydroxyalkoxylation of silylated alkenols
A1 Díez Poza, Carlos
A1 Val Domínguez, Patricia
A1 López Hernández, Enol
A1 Barbero Pérez, María Asunción
K1 2306 Química Orgánica
AB A convenient route for the preparation of tetrahydropyran (THP) derivatives with a quaternary and tertiary vicinal stereocenters is reported. The atom economy acid-catalyzed cyclization of allylsilyl alcohols provided polysubstituted tetrahydropyrans in good yields and excellent diastereoselectivities (>95 : 5). In comparison with the traditional oxymercuration procedure, this approach resulted to be more efficient in both yield and stereocontrol.
PB Wiley
SN 2193-5807
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/75168
UL https://uvadoc.uva.es/handle/10324/75168
LA eng
NO Asian Journal of Organic Chemistry, 2024, vol. 13, n. 7, e202400096
NO Producción Científica
DS UVaDOC
RD 09-mar-2025