RT info:eu-repo/semantics/doctoralThesis T1 Nuevas tecnologías en lenguas electrónicas para evaluar la calidad de productos lácteos A1 Pérez González, Clara A2 Universidad de Valladolid. Escuela de Doctorado K1 Biosensor K1 Sensors K1 Sensores K1 Electronic tongue K1 Lengua electrónica K1 Nanomaterials K1 Nanomateriales K1 33 Ciencias Tecnológicas AB This doctoral thesis focuses on the development of bioelectronic and electronic tongues based on advanced electrochemical sensors and biosensors, with the goal of improving quality control systems for dairy industry applications. These devices enable the detection of key compounds in liquid dairy products, overcoming the limitations of conventional methods by employing innovative technologies such as nanomaterials and enzymatic bioreceptors. The sensors were designed to optimize critical analytical parameters such as sensitivity, selectivity, and reproducibility, and were integrated into sensor networks to form electronic and bioelectronic tongues. The research centers on creating systems capable of analyzing milk samples, identifying adulterations, and assessing product quality through mathematical models that correlate with traditional techniques. The preparation, characterization, and evaluation of these sensors, as well as their implementation in quality control systems, are detailed in the scientific articles that form the core of this thesis.The studies conducted encompass various areas of research, including the design and development of advanced electrochemical sensors based on techniques such as potentiometry, voltammetry and impedance spectroscopy, as well as the integration of nanomaterials to enhance their electrocatalytic properties. Enzymatic biosensors capable of detecting multiple compounds present in milk, such as sugars and organic acids, were also implemented, with their response being optimized through chemical modification of the electrodes. Additionally, this work includes the development of a methodology for analyzing liquid milk samples, focusing on the detection of adulterations and the evaluation of the quality and integrity of the samples. Furthermore, advanced multivariate statistical methods were employed to process data obtained from the electronic tongues and to develop classification and prediction models.This doctoral thesis is structured in six different chapters. Chapter 1 outlines the current challenges in the dairy industry, along with the motivation and objectives of the research. The second chapter reviews the state of the art, highlighting the most advanced technologies in electronic tongues, electrochemical sensors, and biosensors, as well as their application in the food industry. Third chapter presents the research findings through five scientific articles, which describe advancements in the detection of adulterations, the classification of dairy samples, and the optimization of sensors. The fourth chapter offers the general conclusions and future perspectives of the work, emphasizing the contributions to the thesis to technological advancements in the dairy industry. Finally, the fifth and sixth chapters are dedicated to the bibliography and appendices, which include the publications, conferences, and research stays completed during the development of this thesis.The results of this doctoral thesis have allowed the development of new technologies based on electronic and bioelectronic tongues for quality control in the dairy industry. These systems provide an effective alternative to conventional methods, allowing for fast and accurate analysis of dairy products, with direct applications in improving the sector competitiveness and sustainability. The implementation of these technologies in smart production platforms promises to revolutionize quality control, ensuring the authenticity of products in real-time and contributing to the digital transformation of the industry within the framework of Industry 4.0. YR 2025 FD 2025 LK https://uvadoc.uva.es/handle/10324/75326 UL https://uvadoc.uva.es/handle/10324/75326 LA spa NO Escuela de Doctorado DS UVaDOC RD 02-abr-2025