RT info:eu-repo/semantics/doctoralThesis
T1 Complicaciones a largo plazo de la colangiopancreatografía retrógrada endoscópica con esfinterotomía en el tratamiento de patología biliar benigna
A1 Ibañez García, Mercedes
A2 Universidad de Valladolid. Escuela de Doctorado
K1 Sistema biliar- pancreático
K1 Cholangiopancreatography
K1 Colangiopancreatografía
K1 Cholangitis
K1 Colangitis
K1 Choledocolithiasis
K1 Coledocolitiasis
K1 Pancreatitis
K1 Pancreatitis
K1 32 Ciencias Médicas
AB INTRODUCTION AND AIMS: Endoscopic retrograde cholangiopancreatography (ERCP) is the preferred technique for treating pathologies of the bile duct. It has been suggested that this procedure, combined with sphincterotomy, may influence the subsequent development of long-term complications.The main objective of this study was to determine the long-term complications of biliopancreatic disease after ERCP and their potential association with the development of biliopancreatic neoplasms.MATERIALS AND METHODS: This retrospective cohort study included 576 patients who underwent ERCP (referred to as index ERCP) with sphincterotomy for benign biliary disease, with a minimum follow-up period of more than 2 years.RESULTS: The incidence of long-term benign and neoplastic pathologies after ERCP was analyzed. The most common findings were recurrence of choledocholithiasis in 70 patients (12.1%), cholangitis "sine materia" in 27 patients (4.7%), and acute pancreatitis in 8 patients (1.4%). Eight patients (1.4%) developed hepatobiliopancreatic neoplasms, including 4 cases of pancreatic neoplasms (0.7%), 1 cholangiocarcinoma (0.2%), 1 ampulloma (0.2%), and 2 intrahepatic neoplasms (0.3%). Multivariate analysis revealed that age over 50 years, previous biliary surgery, diversion of the bile duct (BD) to the digestive tract, dilation of the BD, stent placement, biopsy, and cholecystectomy were factors associated with an increased risk of long-term benign complications.CONCLUSIONS: ERCP with sphincterotomy is associated with an increased long-term risk of subsequent benign biliopancreatic disease. However, our data does not allow us to establish a direct relationship with the development of biliopancreatic neoplasms.KEYWORDS: Endoscopic retrograde cholangiopancreatography, complications, choledocholithiasis, cholangitis, pancreatitis.
YR 2025
FD 2025
LK https://uvadoc.uva.es/handle/10324/75846
UL https://uvadoc.uva.es/handle/10324/75846
LA spa
NO Escuela de Doctorado
DS UVaDOC
RD 23-jul-2025