RT info:eu-repo/semantics/article
T1 Prospective bioconversion of CO2 and CO into fine chemicals via halophilic purple phototrophic bacteria
A1 Stegman, Samuel
A1 Melkonian, Chrats
A1 Tamarit, Daniel
A1 Huang-Lin, Elisa
A1 Lebrero Fernández, Raquel
A1 Cantera Ruiz De Pellon, Sara
K1 Carbon dioxide
K1 Carbon monoxide
K1 Halophiles
K1 Health ingredients
K1 Purple phototrophic bacteria
K1 23 Química
AB Microbial conversion of cheap and prob-lematic carbon sources, like CO 2 and CO, into finechemicals offers a promising green alternative tonumerous traditionally fossil fuel-based industriessuch as steel, cement, and pharmaceuticals produc-tion. Purple phototrophic bacteria (PPB) are emerg-ing as versatile key players in carbon–neutral systemsdue to their anoxygenic photosynthesis and diversemetabolic capabilities, enabling the transformationof carbon and nutrients into a wide range of valua-ble products. Traditionally positioned to treat organiccarbon and produce medium-value products like bio-plastics and biomass, PPB also exhibit autotrophiccapabilities, enabling the valorization of waste gases,such as CO2 and CO. A key strength of PPB is theirmetabolic and ecological diversity, including spe-cies inhabiting saline environments. Halophilic bac-teria are known producers of valuable chemicalsfor pharmaceutical and medical applications, suchas osmolytes (ectoine, hydroxyectoine), pigments,amino acids (proline) and natural coenzymes (ubiqui-none), yet halophilic PPB remain underexploredin green upcycling processes. This study identifiedhalophilic PPB capable of transforming waste gasesinto health and wellness products. Through a compre-hensive literature review, we compiled a list of halo-philic PPB and mined their genomes for genes linkedto CO₂/CO utilization as carbon sources. Furthergenomic search revealed genes encoding enzymesfor ectoine/hydroxyectoine, proline, ubiquinone, andcarotenoids (lycopene, β-carotene, spirilloxanthin,and spheroidene). We identified 276 genomes of PPBwith the genomic potential to valorise CO₂/CO intohealth-promoting ingredients, highlighting 22 spe-cies capable of producing three or more chemicalssimultaneously. These findings highlight the untappedpotential of halophilic PPB as bio-platforms for sus-tainable pharmaceutical production.
PB Springer
SN 1569-1705
YR 2025
FD 2025
LK https://uvadoc.uva.es/handle/10324/75925
UL https://uvadoc.uva.es/handle/10324/75925
LA eng
NO Reviews in Environmental Science and Bio/Technology, 2025, vol. 24, n.1, p. 29-41
NO Producción Científica
DS UVaDOC
RD 16-jun-2025