RT info:eu-repo/semantics/article T1 Miniaturized solid-phase extraction techniques in sample preparation applied to food matrices: A review A1 Jano, Ana A1 De La Fuente Ballesteros, Adrián A1 Ares Sacristán, Ana María A1 Bernal Yagüe, José Luis K1 Sample preparation K1 Food K1 Solid-phase microextraction K1 Green analytical chemistry K1 Miniaturization K1 Miniaturized sample preparation techniques K1 2301 Química Analítica AB Sample preparation is a critical step in analytical workflows, especially in food analysis, where complex matricesrequire efficient and reliable extraction techniques. Traditionally, methods such as liquid–liquid extraction havebeen widely used. However, the growing need for greener and more sustainable approaches has shifted the focustoward solid-phase extraction (SPE). In recent years, miniaturized SPE techniques have emerged as a powerfulalternative, offering reduced sample and solvent consumption, simplified workflows, and compatibility withmodern analytical platforms. This review explores the development and application of miniaturized SPE methodsin food analysis, discussing key advances, advantages over traditional techniques, and remaining challenges. Thesolid-phase miniaturized techniques covered include solid-phase microextraction, stir-bar sorptive extraction,magnetic solid-phase extraction, immunoaffinity solid-phase extraction, microextraction by packed sorbent,molecularly imprinted solid-phase extraction, and dispersive micro-solid-phase extraction. By summarizing theliterature and providing a critical overview of these approaches, this work highlights the potential of minia-turized SPE as a cornerstone for innovative and sustainable food analysis. PB Elsevier SN 0026-265X YR 2025 FD 2025 LK https://uvadoc.uva.es/handle/10324/76163 UL https://uvadoc.uva.es/handle/10324/76163 LA eng NO Microchemical Journal, 2025, vol. 213, p. 113794 NO Producción Científica DS UVaDOC RD 30-jul-2025