RT info:eu-repo/semantics/article
T1 Embryonic cerebrospinal fluid in brain development: neural progenitor control
A1 Gato Casado, Ángel Luis
A1 Alonso Revuelta, María Isabel
A1 Martín, Cristina
A1 Carnicero Gila, Estela María
A1 Moro Balbás, José Antonio
A1 Fernández Gómez, José María Fidel
A1 Lamus Molina, José Francisco
A1 Desmond, Mary E.
K1 Nervioso central, Sistema
AB Due to the effort of several research teams across theworld, today we have a solid base of knowledge on theliquid contained in the brain cavities, its composition, andbiological roles. Although the cerebrospinal fluid (CSF) isamong the most relevant parts of the central nervous systemfrom the physiological point of view, it seems that itis not a permanent and stable entity because its compositionand biological properties evolve across life. So, we cantalk about different CSFs during the vertebrate life span.In this review, we focus on the CSF in an interesting period,early in vertebrate development before the formationof the choroid plexus. This specific entity is called “embryonicCSF.” Based on the structure of the compartment,CSF composition, origin and circulation, and its interactionwith neuroepithelial precursor cells (the target cells)we can conclude that embryonic CSF is different from theCSF in later developmental stages and from the adult CSF.This article presents arguments that support the singularityof the embryonic CSF, mainly focusing on its influenceon neural precursor behavior during development and inadult life.
PB Karger
SN 0353-9504
YR 2014
FD 2014
LK http://uvadoc.uva.es/handle/10324/7750
UL http://uvadoc.uva.es/handle/10324/7750
LA eng
NO Croat Medical J. Agosto 2014, 55(4) 299-305
NO Producción Científica
DS UVaDOC
RD 19-nov-2024