RT info:eu-repo/semantics/article
T1 Development of a Risk Predictive Model for Erectile Dysfunction at 12 Months after COVID-19 Recovery: A Prospective Observational Study
A1 Natal Alvarez, Fernando
A1 Conde Redondo, María Consuelo
A1 Sierrasesumaga Martin, Nicolás
A1 García Viña, Alejandro
A1 Marfil Peña, Carmen
A1 Bahillo Martínez, Alfonso
A1 Jojoa Acosta, Mario Fernando
A1 Tamayo Gómez, Eduardo
K1 COVID-19
K1 erectile dysfunction
K1 cardiovascular disease
K1 post-acute COVID-19 syndrome
K1 logistic models
AB Objectives: To develop a risk prediction model for the identification of features involved in the prediction of erectile dysfunction (ED) at 12 months following COVID-19 recovery. Methods: We performed an observational prospective multicentre study. Participants were classified according to their history of COVID-19: (I) patients with a past history of COVID-19 and (II) patients without a previous microbiological diagnosis of COVID-19. A total of 361 patients (past history of COVID-19, n = 166; no past history of COVID-19, n = 195) were assessed from January 2022 to March 2023. Patients with a past history of COVID-19 were assessed at 12 months following COVID-19 recovery. The primary outcome measure was ED, assessed through the 5-item International Index of Erectile Function (IIEF-5). Data concerning epidemiologic variables, comorbidities and active treatment were also collected. We performed a binary logistic regression to develop a risk predictive model. Among the models developed, we selected the one with the higher Area Under the Curve (AUC). Results: The median age was 55 years in both groups. The ED prevalence was 55.9% in patients with past history of COVID-19 and 44.1% in those with no past history of COVID-19. The best predictive model developed for ED comprised 40 variables and had an AUC of 0.8. Conclusions: We developed a regression model for the prediction of ED 12 months after COVID-19 recovery. The application of our predictive tool in a community setting could eventually prevent the adverse effects of ED on cardiovascular health and the associated unfavourable economic impact.
PB Multidisciplinary Digital Publishing Institute
SN 2077-0383
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/80181
UL https://uvadoc.uva.es/handle/10324/80181
LA eng
NO Journal of Clinical Medicine, 2024, vol. 13, n. 19. p. 5757
NO Producción Científica
DS UVaDOC
RD 01-dic-2025