RT info:eu-repo/semantics/article
T1 Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states
A1 Zilio, Federico
A1 Gomez-Pilar, Javier
A1 Cao, Shumei
A1 Zhang, Jun
A1 Zang, Di
A1 Qi, Zengxin
A1 Tan, Jiaxing
A1 Hiromi, Tanigawa
A1 Wu, Xuehai
A1 Fogel, Stuart
A1 Huang, Zirui
A1 Hohmann, Matthias R.
A1 Fomina, Tatiana
A1 Synofzik, Matthis
A1 Grosse-Wentrup, Moritz
A1 Owen, Adrian M.
A1 Northoff, Georg
AB The brain exhibits a complex temporal structure which translates into a hierarchy of distinct neural timescales. An open question is how these intrinsic timescales are related to sensory or motor information processing and whether these dynamics have common patterns in different behavioral states. We address these questions by investigating the brain's intrinsic timescales in healthy controls, motor (amyotrophic lateral sclerosis, locked-in syndrome), sensory (anesthesia, unresponsive wakefulness syndrome), and progressive reduction of sensory processing (from awake states over N1, N2, N3). We employed a combination of measures from EEG resting-state data: auto-correlation window (ACW), power spectral density (PSD), and power-law exponent (PLE). Prolonged neural timescales accompanied by a shift towards slower frequencies were observed in the conditions with sensory deficits, but not in conditions with motor deficits. Our results establish that the spontaneous activity's intrinsic neural timescale is related to the neural capacity that specifically supports sensory rather than motor information processing in the healthy brain.
PB Elsevier
SN 1053-8119
YR 2021
FD 2021-02
LK https://uvadoc.uva.es/handle/10324/80519
UL https://uvadoc.uva.es/handle/10324/80519
LA spa
NO Neuroimage. 2021 Feb 1:226:117579.
DS UVaDOC
RD 15-dic-2025