RT info:eu-repo/semantics/article
T1 Phytochemical study of ‘tajy’ (Handroanthus impetiginosus (Mart.) Mattos) and ‘ka’a ovetĩ’ (Luehea divaricata Mart.) extracts
A1 Sánchez-Hernández, Eva
A1 Cáceres-González, Claudia
A1 García-Valdecasas, José Ignacio
A1 Valdez-Ayala, Sintya
A1 Martín-Gil, Jesús
A1 Martín-Ramos, Pablo
K1 antifungal, Botrytis cinerea, contraceptive, Paraguay, phytoconstituents, pink lapacho, whips horse
AB This study explores the phytochemical composition of leaf extracts from Handroanthus impetiginosus (Mart.) Mattos and Luehea divaricata Mart., used in a contraceptive decoction by Mbya-Guarani women. The phytocompounds were identified by gas chro­matography-mass spectrometry, while Fourier-transform infrared spectroscopy, multi-elemental, and thermal analyses were used to characterise plant biomass. Notably, no phytoconstituent supporting the efficacy of these extracts as female contraceptives was found, except for a small amount (0.3%) of sitosterol. Conversely, L. divaricata leaves contained compounds like 1,3-dihydroxyacetone dimer, N-methyl-N-nitroso-2-propanamine, 2-methoxy-N-(2-methoxyethyl)-N-methyl-ethanamine, and 1,3,5-triazine-2,4,6-triamine, potentially exerting cytotoxic, genotoxic, and toxicogenomic effects. Due to the absence of scientific support for the claimed contraceptive efficacy and the presence of safety concerns, we propose an alternative valorisation pathway centred on the presence of phytochemicals exhibiting antimicrobial activity. This proposition is substantiated by their considerable in vitro efficacy against Botrytis cinerea.
SN 1478-6419
YR 2025
FD 2025
LK https://uvadoc.uva.es/handle/10324/80534
UL https://uvadoc.uva.es/handle/10324/80534
LA spa
NO Natural Product Research, 3 July 2025, vol. 39, n.13, p. 3799-3805
DS UVaDOC
RD 12-feb-2026