RT info:eu-repo/semantics/article
T1 Proximate analysis and GC-MS phytochemical profiling of aqueous extracts of Doryopteris raddiana, a plant used by the Mbya-Guaraní as a contraceptive
A1 Sánchez-Hernández, E.
A1 Cáceres-González, C.
A1 Peña-Delgado, V.
A1 García-Valdecasas Medina, J. I.
A1 Casao, A.
A1 Valdez-Ayala, S.
A1 Pérez-Pe, R.
A1 Martín-Gil, J.
A1 Martín-Ramos, P.
K1 amambai′i, fern, fertility, Paraguay, phytoconstituents, spermicide
AB Doryopteris raddiana (Presl) Fée, a traditional contraceptive in Mbya culture, lacks scientific scrutiny regarding its chemical composition and contraceptive efficacy. Employing X-ray fluorescence, Fourier-transform infrared spectroscopy, and thermal analysis, we explored the plant’s organs. Multielemental analysis excluded toxic elements. Key phytoconstituents identified by gas chromatography-mass spectrometry in the extracts obtained through infusion were glycerine, 1,3-dimethyl propane, and catechol in leaves; glycerine, cis-13-octadecenoic acid methyl ester, and 2-deoxy-D-erythro-pentose in stems and roots. Among these chemicals, glycerine emerged as the sole constituent with contraceptive potential, particularly intravaginally. Extract activity tests conducted on ram spermatozoa exhibited a reduction in the percentage of rapid spermatozoa but no significant impact on total motility, progressive motility, or viability. The reported data would only weakly support the advocated contraceptive action of this fern upon vaginal application, not through the oral administration of its decoction.
SN 1478-6419
YR 2025
FD 2025
LK https://uvadoc.uva.es/handle/10324/80535
UL https://uvadoc.uva.es/handle/10324/80535
LA eng
NO Natural Product Research, 2 sept 2025, vol. 39, n.17, p. 4930-4937
DS UVaDOC
RD 15-dic-2025