RT info:eu-repo/semantics/article
T1 Incidence and risk factors of postoperative delirium after surgery in the spanish population: The DELPO study
A1 Varga Martínez, Olga de la
A1 Navarro Pérez, R.
A1 López Herrero, Rocío
A1 Montesinos Fadrique, S.
A1 Almoguera Fernández, J.
A1 Alonso Fernández, M.
A1 Artiaga-Candia, M.
A1 Becerra-Bolaños, A.
A1 Bugueño, N.
A1 Casasempere Sanus, A.
A1 Contreras-López, L.
A1 Cuadrillero Sánchez, R.
A1 De la Rosa-Estadella, M.
A1 de la Torre Riveiro, I.
A1 del Val Peciña, E.
A1 Delgado Martí, C.
A1 Edo Cebollada, L.
A1 Fernández Fernández, R.
A1 Fernández Rodríguez, J.
A1 Ferrer Gómez, C.
A1 Giné Servén, M.
A1 González Pereira, A.
A1 Guereca Gala, A.
A1 Herrera Soto, A.
A1 Illodo Miramontes, G.
A1 Infantes Morales, M.E.
A1 Marcos-Vidal, J.M.
A1 Martínez López, A.
A1 Martínez Ruiz, A.
A1 Martínez-Rafael, B.
A1 Matute González, A.
A1 Pariente Juste, L.
A1 Poves-Álvarez, R.
A1 Regueira Fernández, A.
A1 Renedo Fernández, A.
A1 Rodríguez Álvarez, A.A.
A1 Rodríguez Calvo, A.
A1 Rodríguez Conesa, MA
A1 Sánchez González, C.
A1 Tobar Gonzalo, C.
A1 Varela Rodríguez, L.
A1 Veloso de Sousa, R.
A1 Muñóz-Moreno, M.F.
A1 Escudero Gómez, G.
A1 Tamayo, E.
A1 Varela Duran, M.
A1 Badenes, R.
K1 Delirium
K1 Postoperative delirium
K1 Risk factors
K1 Spain
K1 Surgery
K1 3213 Cirugía
AB Background: Postoperative delirium increases morbidity, mortality, hospital stays, and costs, though 30–40 % ofcases are preventable. This study assessed early delirium incidence in 2442 surgical patients across 43 Spanishhospitals, analyzing it by surgery type and related factors. Conducted from November 14 and 21, 2023, withfollow-ups on days 2 and 60, it provides insights into factors influencing postoperative delirium and outcomes.Methods: The study included three phases: (1) recruitment and assessment of surgical patients on November 14and 21, 2023, across all centers; (2) monitoring for delirium by postoperative day 2; and (3) a follow-up at 60days. Delirium was diagnosed using the CAM, CAM-ICU, and 4AT scales. The sample size was estimated andmultivariable logistic regression and Cox regression analysis were performed to identify independent risk factorsand assess the impact of delirium on mortality.Results: A total of 2442 surgical patients were recruited, mainly male (51.9 %), with a mean age of 76 ± 16 years.The delirium incidence was 3.93 %, with four preoperative independent risk factors identified through multi-variate analysis.: Patient age (odds ratio (OR) 1.05, 95 % CI 1.04 to 1.08, p > 0.001), cognitive impairment (SBT> 6 points) (OR 1.12, 95 % CI 1.08 to 1.15, p < 0.001), substance use disorder (SUD) (OR 3.97, 95 % CI 1.05 to14.93, p = 0.042) and alcoholism (OR 1.92, 95 % CI 1.20 to 3.07, p = 0.006), with a model AUROC of 0.81 (95 %CI 0.76 to 0.85). Postoperative delirium was associated with longer hospital stays and significantly highermortality at 60 days (8.3 % vs 0.6 %).Conclusion: This Spanish study found that postoperative delirium, linked to longer hospital stays and highermortality, requires early detection and prevention to improve outcomes.
PB Elsevier
SN 0952-8180
YR 2025
FD 2025
LK https://uvadoc.uva.es/handle/10324/80944
UL https://uvadoc.uva.es/handle/10324/80944
LA eng
NO Journal of Clinical Anesthesia, 2025, vol. 107, p. 112018
NO Producción Científica
DS UVaDOC
RD 23-dic-2025