RT info:eu-repo/semantics/article T1 Uncaria tomentosa-Loaded Chitosan Oligomers–Hydroxyapatite–Carbon Nitride Nanocarriers for Postharvest Fruit Protection A1 Santiago-Aliste, Alberto A1 Sánchez-Hernández, Eva A1 Buzón-Durán, Laura A1 Marcos-Robles, José Luis A1 Martín-Gil, Jesús A1 Martín-Ramos, Pablo K1 cat’s claw K1 biopolymeric nanoparticles K1 chitosan oligomers K1 g-C3N4 K1 nanoencapsulation K1 natural fungicides K1 postharvest fruit diseases K1 stimuli-responsive systems K1 shelf-life extension K1 sustainable crop protection AB Given the risks associated with synthetic fungicides, it is crucial to explore safe and sustainable alternatives. One potential solution is using bioactive natural products (BNPs). However, BNPs face challenges like lability, solubility, and lack of specificity. These issues can be addressed through nanoencapsulation. This study focuses on the evaluation of novel chitosan oligomers–hydroxyapatite–carbon nitride (COS–HAp–g-C3N4) nanocarriers (NCs) for encapsulating BNPs, specifically an extract from Uncaria tomentosa bark. The NCs were characterized by transmission electron microscopy, energy-dispersive X-ray spectroscopy, and infrared spectroscopy. The NCs were monodisperse, with a mean diameter of 250 nm, and showed an encapsulation efficiency of 82%. The suitability of the loaded NCs (COS–HAp–g-C3N4–BNP, in a 2:1:0.5:1 weight ratio) for postharvest fruit protection was investigated in vitro and ex situ at a laboratory scale. Results regarding their efficacy against Botrytis cinerea on strawberries, Colletotrichum gloeosporioides on mangoes, Penicillium expansum on apples, Monilinia laxa on peaches, and Sclerotinia sclerotiorum on kiwifruit are presented. Minimum inhibitory concentrations of 250, 375, 375, 250, and 187.5 μg·mL−1 were found in vitro, respectively, while higher doses (500, 750, 750, 250, and 375 μg·mL−1, respectively) were needed to achieve effective control in postharvest tests on artificially inoculated fruit. These findings suggest that NCs containing extracts from U. tomentosa bark show promise as biorational agents and as alternatives to conventional fungicides for managing postharvest phytopathogens. PB MDPI SN 2073-4395 YR 2023 FD 2023 LK https://uvadoc.uva.es/handle/10324/81112 UL https://uvadoc.uva.es/handle/10324/81112 LA spa NO Agronomy, 2023, 13(9), 2189 NO Producción Científica DS UVaDOC RD 29-ene-2026