RT info:eu-repo/semantics/article
T1 Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications
A1 Fernández, Sergio
A1 Arnáiz, Virginia
A1 Rufo, Daniel
A1 Arroyo, Yolanda
K1 recursos marinos, aplicaciones terapeúticas, estrategías de síntesis, alcaloides indólicos
K1 indole alkaloids; marine resources; biological activity; therapeutic application; synthetic strategies
K1 3303.05 Síntesis Química
K1 2390.01 Diseño. Síntesis y Estudio Nuevos Fármacos
AB Indole is a versatile pharmacophore widely distributed in bioactive natural products. Thisprivileged scaffold has been found in a variety of molecules isolated from marine organisms suchas algae and sponges. Among these, indole alkaloids represent one of the biggest, most promisingfamily of compounds, having shown a wide range of pharmacological properties including antiinflammatory, antiviral, and anticancer activities. The aim of this review is to show the currentscenario of marine indole alkaloid derivatives, covering not only the most common chemical structuresbut also their promising therapeutic applications as well as the new general synthetic routesdeveloped during the last years.
PB MDPI
YR 2024
FD 2024
LK https://uvadoc.uva.es/handle/10324/81620
UL https://uvadoc.uva.es/handle/10324/81620
LA eng
NO Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications. Marine Drugs, Marzo de 2024, vol. 22, n. 3, p. 126
NO Producción Científica
DS UVaDOC
RD 16-ene-2026