RT info:eu-repo/semantics/article T1 EEGSym: Overcoming Inter-Subject Variability in Motor Imagery Based BCIs With Deep Learning A1 Perez-Velasco, Sergio A1 Santamaria-Vazquez, Eduardo A1 Martinez-Cagigal, Victor A1 Marcos-Martinez, Diego A1 Hornero, Roberto K1 Brain computer interface (BCI), deep learning (DL), motor imagery, transfer learning, inter-subject AB In this study, we present a new Deep Learning (DL) architecture for Motor Imagery (MI) based Brain Computer Interfaces (BCIs) called EEGSym. Our implementation aims to improve previous state-of-the-art performances on MI classification by overcoming inter-subject variability and reducing BCI inefficiency, which has been estimated to affect 10-50% of the population. This convolutional neural network includes the use of inception modules, residual connections and a design that introduces the symmetry of the brain throughthemid-sagittalplane into the network architecture. It is complemented with a data augmentation technique that improves the generalization of the model and with the use of transfer learning across different datasets. We compare EEGSym’s performance on inter-subject MI classification with ShallowConvNet, Deep-ConvNet, EEGNet and EEG-Inception. This comparison is performed on 5 publicly available datasets that include left or right hand motor imagery of 280 subjects. This population isthe largest that has been evaluated in similar studies to date. EEGSym significantly outperforms the baseline models reaching accuracies of 88.6±9.0 on Physionet, 83.3±9.3 on OpenBMI, 85.1±9.5 on Kaya2018, 87.4±8.0 on Meng2019 and 90.2±6.5 on Stieger2021. At the same time, it allows 95.7% of the tested population (268 out of 280 users) to reach BCI control ( 70% accuracy). Furthermore, these results areachieved using only 16 electrodes of themore than 60 available on some datasets. Our implementation of EEGSym, which includes new advances for EEG processing with DL, outperforms previous state-of-the-art approaches on intersubject MI classification. PB IEEE SN 1534-4320 YR 2022 FD 2022-06-27 LK https://uvadoc.uva.es/handle/10324/81636 UL https://uvadoc.uva.es/handle/10324/81636 LA eng NO IEEE Transactions on Neural Systems and Rehabilitation Engineering, vol. 30, pp. 1766-1775, 2022 NO Producción Científica DS UVaDOC RD 16-ene-2026