RT info:eu-repo/semantics/article
T1 Heart rate variability spectrum characteristics in children with sleep apnea
A1 Martín-Montero, Adrián
A1 Gutiérrez-Tobal, Gonzalo C.
A1 Kheirandish-Gozal, Leila
A1 Jiménez-García, Jorge
A1 Álvarez, Daniel
A1 del Campo, Félix
A1 Gozal, David
A1 Hornero, Roberto
K1 3314 Tecnología Médica
K1 3325 Tecnología de las Telecomunicaciones
AB BackgroundClassic spectral analysis of heart rate variability (HRV) in pediatric sleep apnea–hypopnea syndrome (SAHS) traditionally evaluates the very low frequency (VLF: 0–0.04 Hz), low frequency (LF: 0.04–0.15 Hz), and high frequency (HF: 0.15–0.40 Hz) bands. However, specific SAHS-related frequency bands have not been explored.MethodsOne thousand seven hundred and thirty-eight HRV overnight recordings from two pediatric databases (0–13 years) were evaluated. The first one (981 children) served as training set to define new HRV pediatric SAHS-related frequency bands. The associated relative power (RP) were computed in the test set, the Childhood Adenotonsillectomy Trial database (CHAT, 757 children). Their relationships with polysomnographic variables and diagnostic ability were assessed.ResultsTwo new specific spectral bands of pediatric SAHS within 0–0.15 Hz were related to duration of apneic events, number of awakenings, and wakefulness after sleep onset (WASO), while an adaptive individual-specific new band from HF was related to oxyhemoglobin desaturations, arousals, and WASO. Furthermore, these new spectral bands showed improved diagnostic ability than classic HRV.ConclusionsNovel spectral bands provide improved characterization of pediatric SAHS. These findings may pioneer a better understanding of the effects of SAHS on cardiac function and potentially serve as detection biomarkers.
PB Springer Nature
SN 0031-3998
YR 2020
FD 2020-05
LK https://uvadoc.uva.es/handle/10324/81685
UL https://uvadoc.uva.es/handle/10324/81685
LA spa
NO Pediatric Research, Mayo 2020, vol. 89, n. 7, p. 1771-1779
DS UVaDOC
RD 16-ene-2026