RT info:eu-repo/semantics/article
T1 A comparative study of cell behavior on different energetic and bioactive polymeric surfaces made from elastin-like recombinamers
A1 García-Arévalo, Carmen
A1 Pierna, María
A1 Girotti, Alessandra
A1 Arias, Francisco Javier
A1 Rodríguez-Cabello, José Carlos
AB This work explores cell behavior as a function of the topographic (fibers vs. films) and bioactive (RGD inclusion) design of multifunctional surfaces obtained from elastin-like recombinamers (ELRs). The surfaces have been analyzed for their differential roughness, wettability, and surface free-energy, as their precise contribution and importance of controlling critical aspects of cell behavior were investigated. The results suggest that the highest proliferative capacity of cells on the highly hydrophilic surfaces is more closely related to the surface properties than to the presence of adhesion sequences, although they act as an accelerating factor. However, on energetically unfavorable surfaces, bioactivity acquires decisive significance in ensuring cell adhesion and proliferation.
PB Royal Society of Chemistry
SN 1744-683X
YR 2012
FD 2012
LK https://uvadoc.uva.es/handle/10324/82814
UL https://uvadoc.uva.es/handle/10324/82814
LA eng
NO Soft Matter, 2012,8, 3239-3249
DS UVaDOC
RD 25-feb-2026