RT info:eu-repo/semantics/article T1 Cross-contamination pathways in the analysis of plastics and related chemical compounds: Good laboratory practices and tips A1 De La Fuente Ballesteros, Adrián A1 Obaydo, Reem H. A1 Elagamy, Samar H. A1 Ares Sacristán, Ana María A1 Bernal del Nozal, José K1 Plastic K1 Plasticizers K1 Microplastics K1 Contamination K1 Cross-contamination K1 Laboratory practices K1 Trace analysis K1 23 Química AB The analysis of plastics and related chemical compounds, such as plasticizers, flame retardants, and micro- ornanoplastics, often requires working at trace levels, where even minimal contamination can significantly affectresults. However, many of these target analytes are also present in common laboratory materials and environ-ments, increasing the risk of cross-contamination. We identified six major cross-contamination pathwaysfrequently found in analytical workflows: (I) laboratory materials, (II) environmental contamination, (III) humanhandling and manipulation, (IV) solvents and reagents, (V) cleaning and sample preparation, and (VI) instru-mental and system-related contamination. For each of these, preventive measures and good laboratory practicesare suggested based on both experimental experience and examples in the literature. As a general recommen-dation, procedural blanks should be included throughout the analytical process, and contamination risks shouldbe anticipated as early as the experimental design stage. This work provides a structured reference to supportmore reliable and reproducible data generation in the analysis of plastic-related contaminants. Researchers arefurther encouraged to evaluate contamination risks throughout the workflow and to report them transparently intheir publications. PB Elsevier SN 2214-1588 YR 2026 FD 2026 LK https://uvadoc.uva.es/handle/10324/83789 UL https://uvadoc.uva.es/handle/10324/83789 LA eng NO Trends in Environmental Analytical Chemistry, 2026, vol. 50, p. e00304 NO Producción Científica DS UVaDOC RD 25-mar-2026