RT info:eu-repo/semantics/article T1 Health impact assessment of air pollution in Valladolid, Spain A1 Cárdaba Arranz, Mario A1 Muñoz Moreno, María Fe A1 Armentia Medina, Alicia A1 Alonso Capitán, Margarita A1 Carreras Vaquer, Fernando A1 Almaraz Gómez, Ana K1 Higiene ambiental AB To estimate the attributable and targetedavoidable deaths (ADs; TADs) of outdoor air pollution byambient particulate matter (PM10), PM2.5 and O3according to specific WHO methodology.Design: Health impact assessment.Setting: City of Valladolid, Spain (around 300 000residents).Data sources: Demographics; mortality; pollutantconcentrations collected 1999–2008.Main outcome measures: Attributable fractions; ADsand TADs per year for 1999–2008.Results: Higher TADs estimates (shown here) wereobtained when assuming as ‘target’ concentrations WHOAir Quality Guidelines instead of Directive 2008/50/EC.ADs are considered relative to pollutant backgroundlevels. All-cause mortality associated to PM10 (all ages):52 ADs (95%CI 39 to 64); 31 TADs (95%CI 24 to 39).All-cause mortality associated to PM10 (<5 years): 0 ADs(95% CI 0 to 1); 0 TADs (95% CI 0 to 1). All-causemortality associated to PM2.5 (>30 years): 326 ADs(95% CI 217 to 422); 231 TADs (95% CI 153 to 301).Cardiopulmonary and lung cancer mortality associated toPM2.5 (>30 years):▸ Cardiopulmonary: 186 ADs (95% CI 74 to 280);94 TADs (95% CI 36 to 148).▸ Lung cancer : 51 ADs (95% CI 21 to 73); 27 TADs(95% CI 10 to 41).All-cause, respiratory andcardiovascular mortality associated to O3 (all ages):▸ All-cause: 52ADs (95% CI 25 to 77) ; 31 TADs (95%CI 15 to 45).▸ Respiratory: 5ADs (95% CI −2 to 13) ; 3 TADs (95%CI −1 to 8).▸ Cardiovascular: 30 ADs (95% CI 8 to 51) ; 17 TADs(95% CI 5 to 30).Negative estimates which should be read as zero wereobtained when pollutant concentrations were belowcounterfactuals or assumed risk coefficients were belowone.Conclusions: Our estimates suggest a not negligiblenegative impact on mortality of outdoor air pollution. Theimplementation of WHO methodology provides criticalinformation to distinguish an improvement range in airpollution control.INTRODUCTIONNumerous epidemiological studies conducted PB BMJ Publishing Group SN 2044-6055 YR 2014 FD 2014 LK http://uvadoc.uva.es/handle/10324/8392 UL http://uvadoc.uva.es/handle/10324/8392 LA eng NO BMJ Open 2014, vol.4, n.10. p.3-12 NO Producción Científica DS UVaDOC RD 26-abr-2024