RT info:eu-repo/semantics/article
T1 Application of the click analytical chemistry index for the assessment of endocrine-disrupting chemicals in cosmetics and personal care products
A1 De La Fuente Ballesteros, Adrián
A1 Jano Bascones, Ana
A1 Custodio Mendoza, Jorge A.
A1 Samanidou, Victoria
A1 Mansour, Fotouh R.
A1 Ares Sacristán, Ana María
A1 Bernal del Nozal, José
K1 Endocrine-disrupting chemicals
K1 Personal care products
K1 Click Analytical Chemistry Index
K1 Sustainability
K1 Practicality
K1 2301 Química Analítica
AB Cosmetics and personal care products often contain parabens, phthalates, and bisphenols, compounds used as preservatives or plasticizers that may also migrate from packaging materials into the product. Their potential endocrine-disrupting effects have prompted stricter regulations and concentration limits. Given their occurrence and the complexity of cosmetic matrices, several extraction and chromatographic techniques have been developed to ensure reliable quantification. In this review, representative methods published from 2018 to 2025 focused on the determination of these compounds were evaluated using the click analytical chemistry index (CACI), a recently developed color-coded tool that integrates analytical performance, environmental impact, cost, and applicability within a single framework. CACI allows an objective and balanced comparison of analytical methods, emphasizing practicality and real-world feasibility. The obtained CACI scores ranged from 57 to 80, suggesting that the evaluated methodologies can be categorized as acceptable (50-75%) or highly practical (>75%). It is expected that the use of CACI will promote the development of more sustainable, practical, and user-oriented analytical strategies for the evaluation of chromatographic methods, not only for endocrine-disrupting chemicals in cosmetics and personal care products, but also for other substances of interest.
PB Elsevier
SN 0021-9673
YR 2026
FD 2026
LK https://uvadoc.uva.es/handle/10324/84226
UL https://uvadoc.uva.es/handle/10324/84226
LA eng
NO Journal of Chromatography A, 2026, vol. 1778, p. 466990
NO Producción Científica
DS UVaDOC
RD 21-abr-2026