TY - THES A3 - Andrés García, José María A3 - Baszczyňski, Ondřej AU - García Gallardo, María PY - 2020 UR - http://uvadoc.uva.es/handle/10324/43314 AB - Los profármacos de nucleótidos (ProTide) basados en compuestos de fosfato o fosfonato son fármacos antivirales potentes y comercializados con éxito. La estrategia ProTide consiste en enmascarar temporalmente el grupo fosfónico libre polar para que... AB - Nucleotide prodrugs (ProTides) based on phosphate or phosphonate compounds are potent and successfully marketed antiviral drugs. The ProTide strategy temporary masks the polar free phosphonic group facilitating the drug delivery inside the target... LA - eng KW - Drug delivery KW - ProTide KW - Phosphate prodrugs TI - Phosphate based self-immolative linkers aimed for delivery of drugs M3 - info:eu-repo/semantics/bachelorThesis ER -