TY  - THES 
A3  - Cózar Castellano, Irene
A3  - Perdomo Hernández, Germán
AU  - González Casimiro, Carlos Manuel
PY  - 2021
UR  - https://uvadoc.uva.es/handle/10324/60284
AB  - Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed Zn2+-metalloendopeptidase that degrades insulin and glucagon among other substrates. By decades, its main function has been attributed to hepatic insulin clearance, a...
AB  - La enzima degradadora de insulina (IDE) es una Zn2+-metaloendopeptidasa altamente conservada y expresada de forma ubicua que degrada la insulina y el glucagón, entre otros sustratos. Durante décadas, se ha atribuido su función principal al...
LA  - eng
KW  - Diabetes
KW  - Endocrinology
KW  - Insulina hepática
KW  - Hepatic insulin
KW  - Homeostasis de la glucosa
KW  - Glucose homeostasis
KW  - Metabolismo
KW  - Metabolism
TI  - Hepatic insulin-degrading enzyme regulation and its role on glucagon signaling
M3  - info:eu-repo/semantics/doctoralThesis
DO  - 10.35376/10324/60284
ER  -