TY - JOUR AU - Zharikov, Alevtina D. AU - Cannon, Jason R. AU - Tapias, Victor AU - Bai, Qing AU - Horowitz, Max P. AU - Shah, Vipul AU - El Ayadi, Amina AU - Hastings, Teresa G. AU - Greenamyre, J. Timothy AU - Burton, Edward A. PY - 2015 SN - 0021-9738 UR - https://uvadoc.uva.es/handle/10324/63883 AB - Multiple convergent lines of evidence implicate both α-synuclein (encoded by SCNA) and mitochondrial dysfunction in the pathogenesis of sporadic Parkinson's disease (PD). Occupational exposure to the mitochondrial complex I inhibitor rotenone... LA - eng TI - shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson’s disease model DO - 10.1172/JCI64502 ER -