TY  - JOUR 
AU  - Tapias, Victor
AU  - Hu, Xiaoping
AU  - Luk, Kelvin C.
AU  - Sanders, Laurie H.
AU  - Lee, Virginia M.
AU  - Greenamyre, J. Timothy
PY  - 2017
SN  - 1420-682X
UR  - https://uvadoc.uva.es/handle/10324/63888
AB  - Intracellular accumulation of α-synuclein (α-syn) are hallmarks of synucleinopathies, including Parkinson's disease (PD). Exogenous addition of preformed α-syn fibrils (PFFs) into primary hippocampal neurons induced α-syn aggregation and accumulation....
LA  - eng
TI  - Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production
DO  - 10.1007/s00018-017-2541-x
ER  -