TY  - JOUR 
AU  - Fu, Guo
AU  - Casas, Javier
AU  - Rigaud, Stephanie
AU  - Rybakin, Vasily
AU  - Lambolez, Florence
AU  - Brzostek, Joanna
AU  - Hoerter, John A. H.
AU  - Paster, Wolfgang
AU  - Acuto, Oreste
AU  - Cheroutre, Hilde
AU  - Sauer, Karsten
AU  - Gascoigne, Nicholas R. J.
PY  - 2013
SN  - 0028-0836
UR  - https://uvadoc.uva.es/handle/10324/64300
AB  - This work shows that the Themis protein has a critical role in positive and negative thymocyte selection by dampening responses to low-affinity ligands but without affecting responses to high-affinity ligands, thus enabling positive selection of...
LA  - eng
TI  - Themis sets the signal threshold for positive and negative selection in T-cell development
DO  - 10.1038/nature12718
ER  -