TY  - JOUR 
AU  - Wei, Qianru
AU  - Brzostek, Joanna
AU  - Sankaran, Shvetha
AU  - Casas, Javier
AU  - Hew, Lois Shi-Qi
AU  - Yap, Jiawei
AU  - Zhao, Xiang
AU  - Wojciech, Lukasz
AU  - Gascoigne, Nicholas R. J.
PY  - 2020
SN  - 0027-8424
UR  - https://uvadoc.uva.es/handle/10324/64304
AB  - Src family kinase Lck plays critical roles during T cell development and activation, as it phosphorylates the TCR/CD3 complex to initiate TCR signaling. Lck is present either in coreceptor-bound or coreceptor-unbound (free) forms, and we here present...
LA  - eng
TI  - Lck bound to coreceptor is less active than free Lck
DO  - 10.1073/pnas.1913334117
ER  -