TY - JOUR AU - Chareyron, Isabelle AU - Christen, Stefan AU - Moco, Sofia AU - Valsesia, Armand AU - Lassueur, Steve AU - Dayon, Loïc AU - Wollheim, Claes B. AU - Santo Domingo, Jaime AU - Wiederkehr, Andreas PY - 2020 SN - 0012-186X UR - https://uvadoc.uva.es/handle/10324/66019 AB - Aims/hypothesis: In islets from individuals with type 2 diabetes and in islets exposed to chronic elevated glucose, mitochondrial energy metabolism is impaired. Here, we studied early metabolic changes and mitochondrial adaptations in human beta cells... LA - eng PB - Springer Nature KW - diabetes, glucose, human, beta-cell, mitochondria TI - Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells DO - 10.1007/s00125-020-05275-5 ER -