TY - JOUR AU - García Casas, Paloma AU - Álvarez Illera, María Pilar AU - Gómez Orte, Eva AU - Cabello, Juan AU - Fonteriz García, Rosalba Inés AU - Montero Zoccola, María Teresa AU - Álvarez Martín, Javier PY - 2021 SN - 1663-9812 UR - https://uvadoc.uva.es/handle/10324/66082 AB - We have reported recently that the mitochondrial Na+/Ca2+ exchanger inhibitor CGP37157 extends lifespan in Caenorhabditis elegans by a mechanism involving mitochondria, the TOR pathway and the insulin/IGF1 pathway. Here we show that CGP37157... LA - eng PB - Frontiers KW - C. elegans KW - CGP37157 KW - lifespan KW - endoplasmic reticulum KW - mitochondria KW - sarcopenia TI - The mitochondrial Na+/Ca2+ exchanger inhibitor CGP37157 preserves muscle structure and function to increase lifespan and healthspan in Caenorhabditis elegans DO - 10.3389/fphar.2021.695687 ER -