TY - JOUR AU - Lordén, Gema AU - Sanjuán-García, Itziar AU - de Pablo, Nagore AU - Meana, Clara AU - Alvarez-Miguel, Inés AU - Pérez-García, M. Teresa AU - Pelegrín, Pablo AU - Balsinde, Jesús AU - Balboa, María A. PY - 2017 SN - 0022-1007 UR - https://uvadoc.uva.es/handle/10324/79492 AB - Mutations in human LPIN2 produce a disease known as Majeed syndrome, the clinical manifestations of which are ameliorated by strategies that block IL-1β or its receptor. However the role of lipin-2 during IL-1β production remains elusive. We show here... LA - spa TI - Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation DO - 10.1084/jem.20161452 ER -