TY - JOUR AU - Guevara Pulido, James Oswaldo AU - Andrés García, José María AU - Pedrosa Sáez, Rafael PY - 2015 SN - 2046-2069 UR - http://uvadoc.uva.es/handle/10324/21451 AB - The reaction of enals with α,α′-diaryl-substituted acetones (pKa > 18) catalyzed by (S)-1-(2-pyrrolidinylmethyl) pyrrolidine provides direct access to enantioenriched 2,5,6-trisubstituted-3-hydroxy cyclohexanones. The process constitutes a highly... LA - eng PB - Royal Society of Chemistry KW - Química orgánica TI - The organocatalyzed domino Michael–aldol reaction revisited. Synthesis of enantioenriched 3-hydroxycyclohexanone derivatives by reaction of enals with α,α′-diaryl-substituted acetone DO - 10.1039/C5RA11215J ER -