TY  - JOUR 
AU  - Portillo de la Fuente, Ana María
AU  - Prado Santos, Ángel de
AU  - Soares, Ana J.
PY  - 2026
SN  - 0092-8240
UR  - https://uvadoc.uva.es/handle/10324/82745
AB  - Inflammatory bowel disease (IBD), including Crohn s disease (CD) and ulcerative colitis (UC), is characterized by chronic intestinal inflammation driven by elevated tumor necrosis factor-alpha (TNF-α). Infliximab, an anti-TNF-α monoclonal antibody, is...
LA  - eng
PB  - Springer Nature
KW  - Modelos matemáticos
KW  - Biomedicina
KW  - Enfermedad inflamatoria intestinal
KW  - Enfermedad inflamatoria intestinal
KW  - TNF-α
KW  - Infliximab
KW  - Terapia biológica
KW  - Eliminación de fármacos
KW  - Modelización matemática
TI  - A mathematical model to simulate the biological action of Infliximab on TNF-α in patients with Inflammatory Bowel Disease: the critical role of drug clearance
DO  - 10.1007/s11538-026-01603-9
ER  -