TY - JOUR AU - González-Casimiro, Carlos M. AU - Cámara-Torres, Patricia AU - Merino, Beatriz AU - Astudillo, Alma M. AU - de la Fuente, Miguel A. AU - Ramírez, Cristina M. AU - Alonso, Andrés AU - Cózar-Castellano, Irene AU - Perdomo, Germán PY - 2025 UR - https://uvadoc.uva.es/handle/10324/83153 AB - Insulin-degrading enzyme (IDE) is a protein with proteolytic and non-proteolytic functions that regulates glucose homeostasis. In the fasted state, glucagon regulates glycemia through induction of hepatic gluconeogenesis. The rate of hepatic... LA - eng TI - Decreased expression of insulin-degrading enzyme increases gluconeogenesis and glucose production in cultured hepatocytes administered with glucagon DO - 10.1038/S41598-025-03790-2 ER -